SGC Frankfurt


The Structural Genomics Consortium at the Goethe University Frankfurt (SGC Frankfurt) is focused on the development of selective inhibitors (chemical probes), which help us to better understand the biological role of key signaling molecules and may serve as a starting point to target these proteins in different diseases. The SGC Frankfurt is committed to sharing its research in the spirit of Open Science.





January 2018

Stefan Knapp is among the top 10 most cited protein scientist in Europe according to the latest Lab Times ranking, based on an analysis of research articles published between 2009 and 2015 in "protein" research journals. Read more


December 2017
The internationally recognized scientist Ivan Dikic, has announced his intention to remain at the Goethe University Frankfurt rejecting counter offers from abroad. Read more



Chaikuad A, Koch P, Laufer S, Knapp S. Targeting the Protein Kinases Cysteinome. Angew Chem Int Ed Engl. 2017 Link


Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement. Vasta JD, Corona CR, Wilkinson J, Zimprich CA, Hartnett JR, Ingold MR, Zimmerman K, Machleidt T, Kirkland TA, Huwiler KG, Ohana RF, Slater M, Otto P, Cong M, Wells CI, Berger BT, Hanke T, Glas C, Ding K, Drewry DH, Huber KVM, Willson TM, Knapp S, Müller S, Meisenheimer PL, Fan F, Wood KV, Robers MB. Cell Chem Biol. 2017 Link



Susanne Müller-Knapp
Chief Operating Officer
Tel: +49 (0) 69 798-42501
contact (at)

Max-von-Laue-Straße 15,
60438 Frankfurt am Main