SGC Frankfurt


The Structural Genomics Consortium at the Goethe University Frankfurt (SGC Frankfurt) is focused on the development of selective inhibitors (chemical probes), which help us to better understand the biological role of key signaling molecules and may serve as a starting point to target these proteins in different diseases. The SGC Frankfurt is committed to sharing its research in the spirit of Open Science.





June 2019

SGC Frankfurt on Social Media – We happily invite you to follow us on LinkedIn and Twitter! We will keep you updated about upcoming events, recently published papers, collaborations with our partners from industry as well as academia and a lot more.


May 2019

SGC Frankfurt will be hosting the SGC science day 2019 at Goethe University, Riedberg campus, on Thursday, June 6, starting 8:50 am. If you are interested in quality control, chemical tools and application in human disease you are welcome to join the event. For further information please click here.




Stolz A, Dikic I. Elusive mitochondrial connection to inflammation uncovered. Nature. 2018 Link


Drewes G, Knapp S. Chemoproteomics and Chemical Probes for Target Discovery. Trends Biotechnol. 2018 Link


Georgi V, Schiele F, Berger BT, Steffen A, Marin Zapata PA, Briem H, Menz S, Preusse C, Vasta JD, Robers MB, Brands M, Knapp S, Fernández-Montalván A. Binding Kinetics Survey of the Drugged Kinome. J Am Chem Soc. 2018 Link




Susanne Müller-Knapp
Chief Operating Officer
Tel: +49 (0) 69 798-42501
contact (at)

Max-von-Laue-Straße 15,
60438 Frankfurt am Main